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A few specimens have been recorded in Brazil (Roraima). We use cookies to improve your website experience. Neonate and adult C. simus share about 50% of their venom proteome. Snake venom phospholipase A2 (PLA2) that … The ocular disturbances, which according to Alvaro (1939) occur in some 60% of terrificus cases, are sometimes followed by permanent blindness. : 635168, Data Development History and Data Quality, Reptile Database (2017), website (version 24-Dec-16), Campbell, Jonathan A., and William W. Lamar, McDiarmid, Roy W., Jonathan A. Campbell, and T'Shaka A. Touré, Go We report a comparative venomic and antivenomic characterization of the venoms of newborn and adult specimens of the Central American rattlesnake, Crotalus simus, and of the subspecies cumanensis, durissus, ruruima, and terrificus of South American Crotalus durissus. [4] Hemorrhagins may be present in the venom, but any corresponding effects are completely overshadowed by the startling and serious neurotoxic symptoms.[8]. Taxonomic Serial No. 0000008213 00000 n 0000051538 00000 n Alvaro ME.
1939. 0 10, pp.
Crotalus durissus maricelae — QUIJADA-MASCAREÑAS & WÜSTER 2006 Caudisona durissus — HOSER 2009 Crotalus durissus — WÜSTER & BERNILS 2011 Caudisona durissa — HAMDAN et al. 0000006890 00000 n Humboldt, 1811 [4] Currently, 8 subspecies are recognized, including the nominate subspecies described here. Find out more about the company LUMITOS and our team.
It is useful for tracking sequence updates.
However, its range is discontinuous,[1] with many isolated populations in northern South America, including Colombia, Venezuela, Guyana, Suriname, French Guiana and northern Brazil. ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. Neuromuscular effect of venoms from adults and juveniles of. This change do not impact the academic content of the article. 0000002616 00000 n 0000007002 00000 n Crotalus durissus cumanensis es la típica serpiente de cascabel de Venezuela. of multiple genes (paralogs). Purpose: The snakes in Venezuela vary in their different venom composition amid the species. 0000027398 00000 n Other serious complications may result from systemic disorders (incoagulable blood and general spontaneous bleeding), hypotension and shock. We would like to thank two anonymous referees that have helped improving the manuscript.from the sequence. Find out how LUMITOS supports you with online marketing.
,This subsection of the 'Function' section provides information relevant to cofactors. Both venoms exhibited neurotoxic activity in chick biventer cervicis nerve-muscle preparation. 0000020460 00000 n MA, EA and ARA carried out the experiments. durissus. an experiment that has been published in the scientific literature, an orthologous protein, a record from another database, etc.
0000012667 00000 n PDF at Wolfgang Wüster. Myoglobin released into the blood results in dark urine. 0000054489 00000 n 0000002246 00000 n Crotalus durissus is a venomous pitviper species found in South America. Crotalus Linnaeus, 1758 – Rattlesnakes : Species: Crotalus durissus Linnaeus, 1758 – South American Rattlesnake, Víbora-cascabel tropical, Cascabel Rattlesnake, Central American Rattlesnake : Subspecies: Crotalus durissus cumanensis … 0000047125 00000 n 0000013922 00000 n Your browser does not support JavaScript. Results: The lymphocyte response was measured by the Alamar Blue® (Resazurin) assay, observing that the Crotalus crude venom increased basal proliferation in the spleen and lymph nodes, being also increased with ConA and LPS. [1], Bite symptoms are very different from those of Nearctic species[8] due to the presence of neurotoxins (crotoxin and crotamine) that cause progressive paralysis.Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.
In fact, after the previous nominate subspecies for the durissus complex became the current nominate for C. simus, which now represents its Mexican and Central American members, C. d. dryinus became the new nominate for the South American rattlesnakes as represented by C. 0000014868 00000 n
Both venoms exhibited neurotoxic activity in chick biventer cervicis nerve-muscle preparation.
[2] Also occurs on some islands in the Caribbean, including Morro de la Iguana, Tamarindo and Aruba. Wüster W, Ferguson JE, Quijada-Mascareñas JA, Pook CE, Salomão MG, Thorpe RS. 0000005719 00000 n with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018. 0000018355 00000 n 0000016352 00000 n [1], Found in in all South American countries except Ecuador and Chile.
0000018270 00000 n 0000001465 00000 n 0000039361 00000 n Die Schauer-Klapperschlange (Crotalus durissus), auch als Cascabel oder Tropische Klapperschlange bezeichnet, ist die einzige Art der Klapperschlangen (Crotalus), deren Verbreitungsgebiet auf dem … Registered in England & Wales No. ABSTRACT. Both Bc venom and its SPF fraction had no significant effect on basal proliferation in the spleen and lymph nodes, but a decrease in the response with ConA was observed. Crotalus durissus cumanensis is a subspecies endemic to Colombia and Venezuela, particularly abundant in the Caribbean coast, Magdalena River valley and Llanos Orientales regions (15). 991 0 obj <>stream 22, No. :�ޞ���&9���-� YFA�Ј��X� Crotoxin, the major component of the C. d. cumanensisvenom (CDCmV), is responsible for most of its neurotoxic and myotoxic effects (6, 12). Immunotoxicological effects triggered by .... Medicine, Dentistry, Nursing & Allied Health.
), The Reptile Database, (http://www.reptile-database.org), The Venomous Reptiles of the Western Hemisphere, vols. Opth., Vol. Snake Venom in Opthomology. 0000003172 00000 n %%EOF Manual assertion based on experiment ini,
Manual validated information which has been generated by the UniProtKB automatic annotation system.
Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE. 0000006352 00000 n Protein sets from fully sequenced genomes. Am. 935 0 obj <> endobj Database of comparative protein structure models, ProtoNet; Automatic hierarchical classification of proteins, MobiDB: a database of protein disorder and mobility annotations. It also includes information pertinent to the sequence(s), including length and molecular weight. Accessed 28 August 2007. • The juveniles’ venom did not inhibit significantly the ACh and KCl … Crotalus durissus cumanensis The venoms of Crotalus durissus cumanensis, were different.The juveniles’ venom has a faster blockade than adults’ venom. Funding for the research was provided by grant PG: 09-8760-2013, Caracas, Venezuela, from the Consejo de Desarrollo Científico y Humanístico de la Universidad Central de Venezuela, Bolivarian Republic of Venezuela. Copyright © 2020 Elsevier B.V. or its licensors or contributors.
to Advanced Search and Report, Crotalus durissus cumanensis Humboldt, 1811, Uetz, P. & Jirí Hosek (eds. 0000007103 00000 n
dryinus). By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.
Examples: P92958, Q8TDN4, O14734
This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.
,This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.
,This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. This article has been republished with minor change. Crotalus durissus cumanensis, a rattlesnake endemic to Colombia and Venezuela, is considered one of the most lethal snake species in Latin America.The aim of the present study was to compare the protein content and biological activity of the venom obtained from eight specimens of C. durissus cumanensis… The most widely distributed member of its genus, this species poses a serious medical problem in many parts of its range. [8] Phospholipase A2 neurotoxins also cause damage to skeletal muscles and possibly the heart, causing general aches, pain and tenderness throughout the body. Others, such as most vitamins, are organic.
,This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.
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